This year’s edition of the annual meeting of the Sociedade Portuguesa de Imunologia (SPI) will be at the i3S (Instituto de Investigação e Inovação em Saúde), in Porto, from the 14th to 16th of June, 2017.
This meeting has an excellent scientific program. This edition will focus on Infection and Immunity, Cancer Immunology, Mucosal Immunology, and Immunodeficiencies. Which will be enriched with a unique panel of speakers (see details below).
We welcome your participation.
See you there,
The organizing committee,
Nuno L. Alves
Susana Lopes da Silva
Infection and Immunity Session
Maximiliano G. Gutierrez
The Francis Crick Institute, London, UK
Title: The role of phagosomes in the immune response to tuberculosis
Max studied biochemistry and molecular biology in Argentina. In 2005, he was awarded a PhD in cell biology where he focused on the interactions between intracellular pathogens and the autophagic pathway. After that, he was in Gareth Griffiths Laboratory at EMBL, Heidelberg, Germany as a postdoctoral fellow of the von Humboldt foundation and EMBO focusing on the cell biology of macrophages and mycobacteria. In 2009, he became the head of the Junior Research Group “Phagosome Biology” at the Helmholtz Centre for Infection Research in Braunschweig, Germany. In 2012, he was recruited as a Programme Leader Track at the National Institute for Medical Research in London. Since 2015, he is a group leader at the Francis Crick Institute in London where he is developing imaging technologies and cellular models of infection to investigate the host-pathogen interactions in tuberculosis.
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal
Title: Novel molecular mechanisms regulating innate antifungal immunity
Agostinho Carvalho is a biologist and received his PhD in Health Sciences– Biological and Biomedical Sciences, from the University of Minho in 2008. Between 2009 and 2012, he was a Postdoctoral research fellow at the University of Perugia, Italy. In 2012, he was selected for a PhD researcher position of the Department of Experimental Medicine of the University of Perugia, where he acted as a faculty member until 2014. Since then, he is PrincipaI Investigator at ICVS, University of Minho. His research interests are focussed on the dissection of the genetic architecture of antifungal immunity and its role in susceptibility to fungal disease. These aims are being addressed in the lab by resorting to advanced cellular and animal models of fungal infection and by investigating human patients suffering from fungal disease enrolled in national and international consortia. Because of his contributions to the field, he has been awarded with the Jon J. van Rood award by the European Group of Bone and Marrow Transplantation and is currently a member of the Editorial Advisory Board of the Journal of Infectious Diseases. He has also been participating actively in research projects funded by various entities, including coordination of grants from the Fundação para a Ciência e Tecnologia (FCT) and the European Society of Clinical Microbiology and Infectious Disease. Moreover, he is currently engaged in collaborations with several international labs on immunology, functional genomics and biology of fungal infections.
Cancer Immunology Session
Institut Curie, Paris, France
Sebastian Amigorena obtained his PhD in Paris in 1990. After a 3 years post doc at Yale University, he returned to Paris in 1995 and started an Inserm AVENIR group together with Christian Bonnerot. He is the head of the Immunology Department (INSERM U932, “Cancer Immunity”) at the Curie Institute. Sebastian Amigorena’s main scientific interest overlaps immunology and cell biology. In his graduate and post-doctoral studies, he analyzed the functions of IgG receptors and described the molecular basis of their inhibitory properties. Sebastian Amigorena is today an expert in antigen presentation and cross presentation in dendritic cells. He analyzed dendritic cells’ endocytic pathway and described several unique specializations of their phagocytic pathway. Sebastian Amigorena also made significant contributions to the analysis of cytotoxic T cells dynamics in vivo, during the initiation of immune responses in lymph nodes and during the invasion and rejection of solid tumors.
Instituto de Medicina Molecular, University of Lisbon, Portugal
Title: Innate determinants of cancer surveillance and immunotherapy
Bruno Silva-Santos is Vice-Director of iMM Lisboa, and Associate Professor (with Habilitation) of the Faculty of Medicine of the University of Lisbon. He did his PhD in Immunology with Mike Owen at Cancer Research UK (The London Research Institute), and trained as a post-doc with Adrian Hayday at King’s College London. Since establishing his independent group at iMM Lisboa, Bruno Silva-Santos has been funded by Starting and Consolidator Grants from the European Research Council (ERC) and by the European Molecular Biology Organization (EMBO). His research is dedicated mostly to gamma-delta T lymphocytes, having dissected novel molecular mechanisms of effector cell differentiation (Silva-Santos et al. Science 2005; Ribot et al. Nature Immunol 2009; Schmolka et al. Nature Immunol 2013; Munoz-Ruiz et al. Nature Immunol 2016) and tumor cell recognition and targeting (Lança et al. Blood 2010; Correia et al. Blood 2011; Rei et al. PNAS 2014; Silva-Santos et al. Nature Rev Immunol 2015; Almeida et al. Clin Cancer Res 2016). His translational work was recognized with the Pfizer Award for Clinical Research (2009); and led to a start-up company focused on cancer immunotherapy, Lymphact, where he heads the Scientific Council. He serves as editor for various peer-reviewed journals, including OncoImmunology, Frontiers in Immunology and Oncology, and European Journal of Immunology.
Mucosal Immunology Session
BHF-Centre For Cardiovascular Function
Queens Medical Research Institute
University of Edinburgh
Title: Immune and inflammatory functions of Fat-Associated Lymphoid Clusters
Cecile Bénézech completed her PhD on the antitumoral activity of gamma-delta T cells in the laboratory of Richard Breathnach and Marc Bonneville in 2007. Then moved to Birmingham in the laboratory of Jorge Caamano working on lymph node development, the origin of lymph node stromal cells and the role of the Lymphotoxin Beta Receptor. In 2013, joined the BHF-Centre for Cardiovascular Science in Edinburgh as a Chancellor Fellow to start her research group investigating the relationship between immune system and adipose tissue with a particular focus on the study of Fat-asssociated lymphoid clusters.
Salomé S. Pinho
i3S – Institute for Research and Innovation in Health, University of Porto, Portugal
Title: Glycosylation at the interface of immunology and cancer
Salomé Pinho received her D.V.M. from the University of Porto in 2004 and developed her PhD research at the Institute of Molecular Pathology and Immunology of Univ. Porto (IPATIMUP) and at Boston Medical School, MA, USA from 2006 to 2009. She performed her postdoctoral work at IPATIMUP in the glycobiology and disease field. At present, she is Researcher (PI) at IPATIMUP/i3S and affiliated Professor at Faculty of Medicine at University of Porto. Her research activity is focused on the understanding of the role of post-translational modifications by glycosylation in the regulation of key proteins´ functions involved in cancer and in chronic inflammatory conditions, envisioning potential clinical applications. She is author of several publications in international peer-reviewed journals including Nature Reviews Cancer, Oncogene and Human Molecular Genetics. She supervises a research team composed by Post-Docs, PhD students, Master students and young researchers. She is the Principal Investigator of several national/international funded projects in the field of cancer and inflammatory diseases and she is currently cooordinating an investigator-initiative clinical trial in Inflammatory Bowel Disease. She received the Young Investigator Award from the European Association for Cancer Research and is inventor of two patents.
Human Genetic of Infectious Diseases, Imagine Institute, Paris Descartes University, France
Title: Genetic dissection of atypical mycobacterial infectious diseases in human: 20 years of research are not everything
Jacinta Bustamante, MD, PhD, “MCU-PH” (Associate Professor with tenure). She was born in Tucuman, Argentina on June 6, 1968. She obtained her Doctor of Medicine (MD) in 1993. She carried out clinical training in Pediatrics from 1994-1998. She received her PhD in the year 2007, at Paris Descartes University, France. During this time, she carried out molecular and genetic research under the mentorship of Jean-Laurent Casanova. She discovered the first two X-linked genetic aetiologies of Mendelian Susceptibility to Mycobacterial Diseases (mutations of the NEMO and CYBB genes). Since 2008, she has led the team working on genetic predisposition to mycobacterial infection in the laboratory of Drs. Abel and Casanova (GHMI-INSERM 1163, Paris branch). She is also responsible for the diagnosis of chronic granulomatous disease and MSMD in patients attending the Center for the Study of Primary Immunodeficiencies (CEDI) at Necker Hospital for Sick Children. She has made substantial contributions to the field of genetic predisposition to infectious disease, including bacterial and mycobacterial infectious diseases, in humans. She has considerable experience of the establishment and coordination of collaborations. She interacts with the paediatricians and clinicians worldwide and she is involved with the coordination of the recruitment of MSMD and CGD patients, the collection of clinical information and biological samples and providing feedback in terms of results. She has published over 100 papers in peer-reviewed scientific journals and books.
Lab of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris Descartes University, Imagine Institute, Paris, France
Title: Human genetics of fungal diseases
(Deadline: May 10th)
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1 Student (Undergraduate, BSc, MSc student, MSc, PhD student and Medical Intern)
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To attend the congress dinner on the 15th of June, there is an additional fee of 15€.
Certificates of Attendance will be sent by e-mail after the meeting.
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How to get there
Rua Alfredo Allen, 208, Porto, Portugal – 41°10’33″N 8°36’11”W – View in Google Maps
HF Tuela PortoSingle Standard ***
HF Tuela PortoTwin Standard ***
HF Ipanema ParkSingle Standard *****
HF Ipanema ParkTwin Standard *****
Note: These prices are valid for bookings from the 13th to the 17th of June 2017
Axis Porto Business & SPA HotelSingle Standard ****
Reservation code: SPI2017
Axis Porto Business & SPA HotelTwin Standard ****
Reservation code: SPI2017