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Board of Directors
The Portuguese Society for Immunology Board of Direction
The SPI board of direction have legal responsibilities and must ensure the Society is well-run, financially sound, and that it meets its objectives. As outlined in the SPI rules, each Board is elected by the membership and serves for a three-year period.
Details of the Board of Direction
Margarida Saraiva obtained a degree in Biochemistry in 1997 by Faculdade de Ciências da Universidade do Porto, Portugal. After 4 years (1999-2002) of research on Poxvirus Immune Evasion, in Antono Alcami’s lab, at Cambridge University (UK), Margarida was awarded her PhD. She then moved to Anne O’Garra’s lab, at the National Instiute for Medical Research (London), where she investigated the molecular mechanisms that regulate the expression of Interleukin-10 by immune cells. In 2007, Margarida returned to Portugal and joined the Health Sciences Research Institute (ICVS) at Universidade do Minho (Braga), as a Ciência 2007 fellow. Since June 2015, Margarida leads the Immune Regulation group at IBMC (Porto), dedicated to the study of host and pathogen molecular mechanisms in place during the innate immune response to mycobacteria.
Immune Regulation (IBMC-associated group)
I3S-IBMC, Universidade do Porto
Vice - President
Nuno L. ALves has a Master in Biology from the University of Porto and a Ph.D. in Immunology from the University of Amsterdam. Throughout his career as Immunologist, he has been interested in the mechanisms underlying the homeostasis of T cells, which represent a chief arm of the immune system. Following his Ph.D. at the Academic Medical Centre in Amsterdam, he developed his post-doctoral research at the Institut Pasteur in Paris. Currently, he holds the position of Principal Investigator at the IBMC/I3S in Porto. His research has focused on the thymus, the generative organ for T-cell production. Particularly, his laboratory is focused in studying the differentiation of thymic epithelial cells (TECs), which play a prominent role in T-cell development and in the establishment of immune tolerance.
Thymus Development and Function,
I3S-IBMC, Universidade do Porto
Karine Serre received her PhD from the Centre d’Immunologie de Marseille-Luminy (Université de la Méditerranée – France) in 2002, for her research on antigen delivery on dendritic cells with liposomes for optimal activation of CD4 and CD8 T cells. Then she pursued a post-doctoral training at the MRC Centre for Immune Regulation in the laboratory of Professor Ian MacLennan (University of Birmingham – UK). Her work focused on dissecting the molecular determinants governing the emergence of Th2 and TFh cells in vivo in response to immunization with alum-conjugated antigen. In 2011 she joined the laboratory of Bruno Silva-Santos at the Instituto de Medicina Molecular | João Lobo Antunes (iMM|JLA, Lisbon Portugal) to study the transcriptional regulation of T cells. She is currently a consolidator researcher of the FCT investigator programme, and leads a line of research dedicated to lymphoid-myeloid interactions in the tumour microenvironment. (https://www.immunology.kserre.net/).
Anti-Tumour Myeloid Cell Responses
Instituto de Medicina Molecular | João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa
Agostinho Carvalho is a biologist and received his PhD in Health Sciences – Biological and Biomedical Sciences, from the University of Minho (Braga) in 2008, for his research on the identification and functional characterization of human genetic variation in Toll-like receptors. He then pursued a post-doc at the University of Perugia, Italy, and the Life and Health Sciences Research Institute (ICVS) at University of Minho. His work focused on the genetic analysis of innate immune receptors and molecules involved in antifungal immunity. Since 2014, he is an Assistant Researcher at ICVS. His main areas of research are: the regulatory effects of interindividual genetic variation on molecular and cellular processes of antifungal immunity; identification of novel prognostic, diagnostic and therapeutic targets for the development of personalized medical interventions in patients at-risk of fungal disease. He leads a team with a strong background on identifying genetic markers of susceptibility to infection and dissecting host mechanisms influencing the recognition and the activation of innate immunity to fungal pathogens. (http://www.icvs.uminho.pt/about-icvs/people/agostinhocarvalho)
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal, and ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal
Vera C. Martins is an expert in T lymphocyte and thymus development. She has a degree in Microbiology and Genetics from the Faculty of Sciences, University of Lisbon. Vera obtained her PhD at the Max Planck Institute of Immunobiology and Epigenetics with Thomas Boehm (Freiburg, Germany), where she worked on T lineage commitment and central tolerance induction in the thymus. As a postdoctoral fellow, Vera worked at the University of Ulm and at the German Cancer Research Cancer with Hans-Reimer Rodewald (Ulm and Heidelberg, Germany), where they broke a central dogma in thymus biology by showing that the thymus has cells capable of self-renewal. Furthermore, her work uncovered that those cells undergo leukemogenesis as a consequence of impaired cell competition in the thymus. Vera heads a research group at Instituto Gulbenkian de Ciência since September 2015, which studies the development of T lymphocytes, both in physiological conditions and in malignancy, specifically in T cell acute lymphoblastic leukemia.
Lymphocyte development and leukemogenesis lab, Instituto Gulbenkian de Ciência